View our research and studies on Prevagen®

Prevagen significantly improves memory

Prevagen® significantly improves memory*

Prevagen improves cognitive performance

In a large three month randomized, double-blind, placebo-controlled study of participants over 40 years old who were experiencing some mild memory problems associated with aging, the Prevagen group significantly supported areas of cognitive function such as learning and word recall.* The study was conducted on specific areas of cognitive function using a quantitative, computerized cognitive assessment tool.
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One Card Learning

Effects Of The Calcium Binding Protein Apoaequorin On Memory And Cognitive Function In Older Adults

Effects of Calcium Binding Protein Apoaequorin

A sample of 218 adults, aged 40 to 91 years, with self-reported memory concerns were randomly assigned to receive either apoaequorin or a matched placebo. The apoaequorin arm (10 mg oral) showed a statistically significant improvement in a number of different measures of cognitive function, including executive function, visual and verbal learning, and memory.* Significant improvements were seen on a number of different tasks from the CogState Research Battery. Data was presented/published in 2011 at the ICAD/AAIC in Paris, France.
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Percent of Participants Experiencing Improvement

Prevagen improves memory in a 90 day study*

Impact of Prevagen on Memory

The Prevagen Memory Study was an open-label study of 56 generally healthy participants over a 90 day period measuring changes in overall cognition and general health. Changes in performance were measured via a standardized battery of questions. The results of the study show improved performance across all parameters.
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A Novel Mechanism for Cognitive Enhancement in Aged Dogs"

A Novel Mechanism for Cognitive Enhancement in Aged Dogs

Journal of Veterinary Behavior

A peer reviewed journal article related to the two canine clinical trials featuring apoaequorin’s effect on cognition in aged beagles was accepted for publication by the Journal of Veterinary Behavior in 2014. This study examined the effectiveness of apoaequorin, a calcium buffering protein, in modifying cognitive decline in aged beagle dogs in two separate experiments.
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Enhancement of Cognitive Function

Enhancement of Cognitive Function in Aged Canines with Apoaequorin*

Enhancement of Cognitive Function in Aged Canines with Apoaequorin

These results, suggest the calcium binding protein apoaequorin may have beneficial effects in treating cognitive dysfunction in aged beagle dogs. Initial data was previously presented/published in 2011 at the ICAD/AAIC in Paris, France.
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Safety Assessment Of Apoaequorin*

Food and Chemical Toxicology

Dosing in the study was the equivalent of 4,000 times the recommended daily amount of Prevagen 10mg and 2,000 times the recommended daily amount of Prevagen Extra Strength 20mg. In addition, apoaequorin achieved self-affirmed GRAS status (generally recognized as safe) after an independent panel of expert scientists concluded that apoaequorin is safe for use in food products.
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Safety Assessment Of The Calcium-Binding Protein, Apoaequorin*

Regulatory Toxicology and Pharmacology

Apoaequorin is not expected to have any significant risk of allergic cross-reactivity for those who are allergic to known allergens. The results from the bioinformatics searches with the apoaequorin sequence show the protein is not a known allergen and not likely to cross-react with known allergens.
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Ongoing Reasearch Partnership

University of Wisconsin-Milwaukee Neuroscience

Quincy Bioscience has had a long standing sponsored research agreement with the UWM Neuroscience department and the laboratory of Dr. James R. Moyer. The UWM lab has provided critical insight into the interaction between apoaequorin and hippocampal neurons in animal models. The lab has published and presented several papers at international neuroscience conferences related to apoaequorin and its functionality.

Protein Chemistry

Apoaequorin is capable of crossing the blood brain barrier (BBB) and the GI barrier

When cerebrospinal fluid (CSF) and blood plasma samples were taken from a population of dogs to which apoaequorin was orally administered, these samples showed quantifiable evidence that the supplement was present in the nervous and circulatory systems of the animals. Using a specially designed enzyme-linked immunosorbent assay (ELISA) linked to an electrochemiluminescent assay, it was also demonstrated that apoaequorin levels in dog CSF and plasma increased proportionately as a function of time. These data indicate that apoaequorin is capable of crossing the blood brain barrier and the gastrointestinal barrier via its presence in dog CSF and blood plasma, respectively.

As we age, we lose about 85,000 brain cells each day.

Aging and how Prevagen® can help

In the United States, 10,000 baby boomers turn 50 every day. And although a touch of gray hair can look distinguished, there are other age-related issues that may be unwanted, such as the mild memory problems associated with aging. Your brain is made up of many small cells, and controls everything you do. To stay healthy your brain contains proteins that support brain health.

As we age, the body’s ability to naturally produce this protein slows down. When this happens you may start to experience difficulty with memory, focus and concentration. Prevagen helps support brain cells by supplementing the proteins with the patented ingredient apoaequorin and supports healthier brain function.*

Researchers have discovered a protein that actually supports healthy brain function*

For many years, researchers have known that the human brain loses cells throughout our lives, part of the natural process of aging. In fact, we lose about 85,000 brain cells per day, that is one per second, over 31 million brain cells every year! This impacts every aspect of your life … how you think and how you feel. Recently, scientists made a significant breakthrough in brain health with the discovery that apoaequorin can support healthy brain function, help you have a sharper mind and think clearer.*

Prevagen Supports:

Healthy Brain Function*

Apoaequorin is in the same family of proteins as those found in humans, but it was originally discovered in one of nature’s simplest organisms — the jellyfish.

Sharper Mind*

Now produced in a scientific process, researchers formulated this vital protein into a product called Prevagen®. Prevagen is clinically shown to help with mild memory problems associated with aging.*

Better Memory*

This type of protein is vital and found naturally in the human brain and nervous system. As we age we can’t make enough of them to keep up with the brain’s demands. Prevagen supplements these proteins during the natural process of aging to keep your brain healthy. Prevagen comes in an easy to swallow capsule. It has no significant side effects and will not interact with your current medication.

Clearer Thinking*

Just how well does Prevagen work? In a computer assessed, double-blinded, placebo controlled study, Prevagen improved memory for most subjects within 90 days.*