Results from the Madison Memory Study
We report here on a double-blind, placebo controlled study designed to assess the effect of a apoaequorin supplement, compared to placebo, on specific areas of cognitive functioning using
quantitative, computerized assessments. In a recent double-blind, placebo-controlled trial, older adults taking an apoaequorin supplement reported improvements in memory.*
Methods
A total of 218 adults, aged 40 to 91 years, who had self-reported mild memory concerns associated with aging were randomly assigned to receive a 90 day supply of either apoaequorin 10 mg daily or a matched placebo. Participants were tested at predetermined time points using computer-based assessments from CogState Ltd (www.cogstate.com). Changes on specific assessments of cognitive function were measured at various time points during the study.
Groton Maze Learning
There was a significant change over time between Baseline/Day 0 and Day 90 within the Prevagen® arm, with a decrease in total errors by 18.81%
One Card Learning
The Prevagen® arm saw a significant change from Baseline/Day 0 to Day 90, with 61.47% of participants showing an improvement from the Baseline/Day 0 to Day 90 as measured by the accuracy of performance.
Shopping List Recall
There was a significant difference over time between the total number of correct responses on the Shopping List Recall for participants who were within the normal cognitive range (0 to 1) and for participants within mild to moderate range (2 to 5).
